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San Francisco 49ers 5-5
Channel: NBC BUF -3 O/U 47.5
Buffalo Bills 9-2

San Francisco 49ers @ Buffalo Bills Lines and Odds

Bet Type Spread
  • Spread
  • Total
  • Moneyline
481 49ers 5-5-0 +3.5 -110 + +3 even + -1.5 -120 +
482 Bills 9-2-0 -3.5 -110 + -3 -120 + +1.5 -120 +
481 49ers 5-5-0 o47 -110 + o47.5 -110 + o47.5 -120 +
482 Bills 9-2-0 u47 -110 + u47.5 -110 + u47.5 -120 +
481 49ers 5-5-0 +140 + +140 +
482 Bills 9-2-0 -165 + -166 +
  • SF (+3) % of Bets BUF (-3) 67% 33% 67% 33% % of Money
  • Over (o47.5) % of Bets Under (u47.5) 71% 29% 79% 21% % of Money
  • Betting
  • Scoring
  • Powerline
 
 
481 49ers 5-5-0
482 Bills 9-2-0
Betting
Line SU ATS O/U
o47.5 5-5 4-6 5-5
-3 9-2 7-4 7-4
Scoring
PPG OPPG
25 22.2
29.09 19.45
Powerline Rating i The Powerline rating compares the current line against a stat-driven estimated line and highlights value opportunities.
Current Estimate Edge

Head-to-Head Series History

Bills
vs.
49ers

49ers are 5-5 (50%) in moneyline bets in their last 10 games against BUF for -0.45 total units lost

Bet against SF Moneyline
Bills
vs.
49ers

49ers are 4-6 (40%) in spread bets in their last 10 games against BUF for -2.36 total units lost

Bet against SF Spread
Bills
vs.
49ers

49ers are 6-4 (60%) in over bets in their last 10 games against BUF for 1.45 total units won

Bet on Over
PS ML Team Opp ML PS Score O/U
  • SU
  • ATS
  • O/U
Desc
Trend
Last 3 Games
Last 5 Games
Last 10 Games
Last 3 Home Games
Last 5 Home Games
Last 10 Home Games
Last 3 Away Games
Last 5 Away Games
Last 10 Away Games
Last 3 Games as Favorite
Last 5 Games as Favorite
Last 10 Games as Favorite
Last 3 Games as Underdog
Last 5 Games as Underdog
Last 10 Games as Underdog
Last 3 Games vs BUF
Last 5 Games vs BUF
Last 10 Games vs BUF
Last 3 Home Games vs BUF
Last 5 Home Games vs BUF
Last 10 Home Games vs BUF
Last 3 Away Games vs BUF
Last 5 Away Games vs BUF
Last 10 Away Games vs BUF
Last 3 Games as Favorite vs BUF
Last 5 Games as Favorite vs BUF
Last 10 Games as Favorite vs BUF
Last 3 Games as Underdog vs BUF
Last 5 Games as Underdog vs BUF
Last 10 Games as Underdog vs BUF
Straight-Up
SU W%
2-1 66.7%
3-2 60%
5-5 50%
1-2 33.3%
2-3 40%
5-5 50%
2-1 66.7%
2-3 40%
7-3 70%
2-1 66.7%
3-2 60%
5-5 50%
1-2 33.3%
2-3 40%
5-5 50%
1-2 33.3%
2-3 40%
5-5 50%
1-2 33.3%
3-2 60%
4-3 57.1%
1-2 33.3%
1-2 33.3%
1-2 33.3%
2-1 66.7%
3-2 60%
4-3 57.1%
1-2 33.3%
1-2 33.3%
1-2 33.3%
Against the Spread
ATS W% Units
1-2 33.3% -1.09
2-3 40% -1.18
4-6 40% -2.36
1-2 33.3% -1.09
2-3 40% -1.18
3-7 30% -4.27
1-2 33.3% -1.09
1-4 20% -3.09
6-4 60% +1.45
1-2 33.3% -1.09
2-3 40% -1.18
4-6 40% -2.36
1-2 33.3% -1.09
3-2 60% +0.73
7-3 70% +3.36
1-2 33.3% -1.09
2-3 40% -1.18
4-6 40% -2.36
1-2 33.3% -1.09
2-3 40% -1.18
3-4 42.9% -1.27
1-2 33.3% -1.09
1-2 33.3% -1.09
1-2 33.3% -1.09
2-1 66.7% +0.82
2-3 40% -1.18
3-4 42.9% -1.27
1-2 33.3% -1.09
1-2 33.3% -1.09
1-2 33.3% -1.09
Over/Under
O/U O% U%
1-2 33.3% 66.7%
2-3 40% 60%
5-5 50% 50%
1-2 33.3% 66.7%
2-3 40% 60%
6-4 60% 40%
2-1 66.7% 33.3%
2-2 50% 50%
5-4 55% 45%
1-2 33.3% 66.7%
2-3 40% 60%
5-5 50% 50%
2-1 66.7% 33.3%
2-3 40% 60%
4-6 40% 60%
3-0 100% 0%
4-1 80% 20%
6-4 60% 40%
3-0 100% 0%
3-2 60% 40%
4-3 57.1% 42.9%
2-1 66.7% 33.3%
2-1 66.7% 33.3%
2-1 66.7% 33.3%
2-1 66.7% 33.3%
3-2 60% 40%
4-3 57.1% 42.9%
2-1 66.7% 33.3%
2-1 66.7% 33.3%
2-1 66.7% 33.3%

SF 49ers

  • Trent Williams (OT) Williams did not practice on Wednesday heading into Week 12 versus the Packers. 11/20 · Questionable · Ankle
  • Jon Feliciano (G) The 49ers have opened the 21-day practice window for Feliciano as they await his return from the injured reserve list. 08/28 · Questionable · Knee
  • Javon Hargrave (DL) Hargrave is dealing with a Triceps injury and has been placed on the injured reserve list. He will miss at least four games. 09/22 · Out · Triceps
  • Christian McCaffrey (RB) McCaffrey did not practice on Wednesday heading into Week 12 versus the Packers. 11/20 · Questionable · Achilles
  • George Kittle (TE) Kittle was limited in practice on Wednesday heading into Week 12 versus the Packers. 11/13 · Questionable · Hamstring
  • Charvarius Ward (CB) Ward was limited in practice on Wednesday heading into Week 12 versus the Packers. 11/06 · Questionable · Personal
  • Nick Bosa (DL) Bosa did not practice on Wednesday heading into Week 12 versus the Packers. 11/17 · Questionable · Hip/Oblique
  • Kevin Givens (DL) Givens did not practice on Wednesday heading into Week 12 versus the Packers. 10/23 · Questionable · Groin
  • Dre Greenlaw (LB) Greenlaw is dealing with a torn Achilles and has been placed on the physically unable to perform list. He will miss at least four games. 02/11 · Out · Achilles
  • Mitch Wishnowsky (P) Wishnowsky is dealing with a back injury and has been placed on the injured reserve list. He will miss at least the next 4 games. 11/13 · Out · Back
  • Brandon Aiyuk (WR) Aiyuk has been placed on the injured reserve list. He is expected to miss the remainder of the 2024-25 season. 10/20 · Out · Knee
  • Elijah Mitchell (RB) Mitchell is dealing with a hamstring injury and has been placed on the injured reserve list. He will miss the 2024-25 season. 08/27 · Out · Hamstring
  • Ambry Thomas (CB) Thomas suffered a broken forearm and has been placed on the injured reserve list. He will miss at least four games. 08/10 · Out · Forearm
  • Talanoa Hufanga (S) Hufanga suffered torn wrist ligaments and has been placed on the injured reserve list. He is expected to miss the remainder of the 2024-25 season. 10/06 · Out · Wrist
  • Curtis Robinson (LB) Robinson is dealing with a Knee injury and has been placed on the injured reserve list. He will miss at least four games. 09/26 · Out · Knee
  • Brock Purdy (QB) Purdy was limited in practice on Wednesday heading into Week 12 versus the Packers. 11/20 · Questionable · Shoulder
  • Drake Jackson (DL) Jackson is dealing with a knee injury and has been placed on the physically unable to perform list. He is expected to miss the 2024-25 season. 11/08 · Out · Knee
  • Darrell Luter Jr. (CB) Luter Jr. is dealing with a pelvis injury and has been placed on the injured reserve list. He will miss at least the next 4 games. 11/15 · Out · Pelvis
  • Jacob Cowing (WR) Cowing was limited in practice on Wednesday heading into Week 12 versus the Packers. 11/17 · Questionable · Concussion
  • Tatum Bethune (LB) Bethune has been ruled out heading into Week 12 versus the Packers. 11/17 · Out · Knee
  • SU
  • ATS
  • O/U
Desc
Trend
Last 3 Games
Last 5 Games
Last 10 Games
Last 3 Home Games
Last 5 Home Games
Last 10 Home Games
Last 3 Away Games
Last 5 Away Games
Last 10 Away Games
Last 3 Games as Favorite
Last 5 Games as Favorite
Last 10 Games as Favorite
Last 3 Games as Underdog
Last 5 Games as Underdog
Last 10 Games as Underdog
Last 3 Games vs SF
Last 5 Games vs SF
Last 10 Games vs SF
Last 3 Home Games vs SF
Last 5 Home Games vs SF
Last 10 Home Games vs SF
Last 3 Away Games vs SF
Last 5 Away Games vs SF
Last 10 Away Games vs SF
Last 3 Games as Favorite vs SF
Last 5 Games as Favorite vs SF
Last 10 Games as Favorite vs SF
Last 3 Games as Underdog vs SF
Last 5 Games as Underdog vs SF
Last 10 Games as Underdog vs SF
Straight-Up
SU W%
3-0 100%
5-0 100%
8-2 80%
3-0 100%
5-0 100%
9-1 90%
3-0 100%
3-2 60%
7-3 70%
3-0 100%
5-0 100%
9-1 90%
1-2 33.3%
2-3 40%
4-6 40%
2-1 66.7%
3-2 60%
5-5 50%
2-1 66.7%
2-1 66.7%
2-1 66.7%
2-1 66.7%
2-3 40%
3-4 42.9%
2-1 66.7%
2-1 66.7%
2-1 66.7%
1-2 33.3%
2-3 40%
3-4 42.9%
Against the Spread
ATS W% Units
2-1 66.7% +0.82
4-1 80% +2.64
7-3 70% +3.36
2-1 66.7% +0.82
3-2 60% +0.73
6-4 60% +1.45
3-0 100% +2.73
3-2 60% +0.73
6-4 60% +1.45
2-1 66.7% +0.82
4-1 80% +2.64
7-3 70% +3.36
1-2 33.3% -1.09
2-3 40% -1.18
4-6 40% -2.36
2-1 66.7% +0.82
3-2 60% +0.73
6-4 60% +1.45
2-1 66.7% +0.82
2-1 66.7% +0.82
2-1 66.7% +0.82
2-1 66.7% +0.82
3-2 60% +0.73
4-3 57.1% +0.64
2-1 66.7% +0.82
2-1 66.7% +0.82
2-1 66.7% +0.82
1-2 33.3% -1.09
3-2 60% +0.73
4-3 57.1% +0.64
Over/Under
O/U O% U%
3-0 100% 0%
4-1 80% 20%
6-4 60% 40%
3-0 100% 0%
5-0 100% 0%
8-2 80% 20%
2-1 66.7% 33.3%
2-3 40% 60%
4-6 40% 60%
3-0 100% 0%
4-1 80% 20%
9-1 90% 10%
0-3 0% 100%
1-4 20% 80%
5-5 50% 50%
3-0 100% 0%
4-1 80% 20%
6-4 60% 40%
2-1 66.7% 33.3%
2-1 66.7% 33.3%
2-1 66.7% 33.3%
3-0 100% 0%
3-2 60% 40%
4-3 57.1% 42.9%
2-1 66.7% 33.3%
2-1 66.7% 33.3%
2-1 66.7% 33.3%
2-1 66.7% 33.3%
3-2 60% 40%
4-3 57.1% 42.9%

BUF Bills

  • Dawuane Smoot (DE) Smoot is dealing with a wrist injury and has been placed on the injured reserve list. He will miss at least four games. 11/03 · Out · Wrist
  • Matt Milano (LB) The Bills have opened the 21-day practice window for Milano as they await his return from the injured reserve list. 08/15 · Questionable · Bicep
  • Shane Buechele (QB) Buechele is dealing with a neck injury and has been placed on the injured reserve list. He will miss the entire 2024-25 season. 08/13 · Out · Neck
  • Spencer Brown (OT) Week 13 11/13 · Questionable · Ankle
  • Tommy Doyle (OT) Doyle is dealing with an undisclosed injury and has been placed on the physically unable to perform list. He will miss at least four games. 06/05 · Out · Undisclosed
  • Baylon Spector (LB) Spector is dealing with a calf injury and has been placed on the injured reserve list. He will miss at least four games. 11/08 · Out · Calf
  • Dalton Kincaid (TE) Week 13 11/10 · Questionable · Knee
  • Keon Coleman (WR) Week 13 11/03 · Questionable · Wrist
  • DeWayne Carter (DT) Carter is dealing with a wrist injury and has been placed on the injured reserve list. He will miss at least four games. 10/23 · Out · Wrist
  • Tylan Grable (OT) Grable is dealing with a groin injury and has been added to the injured reserve list. He will miss at least four games. 09/25 · Out · Groin
  • Travis Clayton (OT) Clayton is dealing with a shoulder injury and has been placed on the injured reserve list. He will miss the entire 2024-25 season. 08/27 · Out · Shoulder